Tuesday 28 July 2009

New Informa Healthcare website

Informa Healthcare has moved this week the content of its 180 peer-reviewed journals to a new online delivery platform at www.informahealthcare.com.

The site combines all the Informa Healthcare journal titles listed on InformaWorld.com and InformaPharmaScience.com to help simplify the customer experience. The new site utilizes the online content management and delivery system provided by Atypon Systems, Inc. – an e-publishing solutions supplier for a number of leading information providers including JSTOR, New England Journal of Medicine and the American Chemical Society.

The Atypon system enables Informa Healthcare to integrate a comprehensive archive service dating back to 1918 giving pharmaceutical, medical and healthcare professionals one central, high-quality source of information.

The new platform offers the option of online trials, advanced searching, alerting, and single article purchases. The site also provides COUNTER-compliant reports and statistics to help subscribers analyze usage.

There will be a dual-hosting period with the InformaWorld platform, which currently hosts the medical content, through 2009 allowing for a gradual migration. Informa Healthcare will set up customer accounts in August and will notify subscribers of the change to ensure a seamless transition to the new site. Customers with journals on InformaPharmaScience.com will be automatically re-directed.

This website will also allow Informa Healthcare to implement new features and improve the layout over the next few months.

To review a list of journal titles on the new site or for more information, visit www.informahealthcare.com.

Monday 13 July 2009

Ubiquitin - a promising target for new drug development

Where potential approaches to drug discovery are concerned, ubiquitylation might not be the first word that springs to mind. But the 2006 approval of bortezomib (Velcade) and recent research into inhibitors of the ubiquitin-proteasome pathway have raised expectations for this biological process as a target for novel treatments for a range of diseases.

A recent review article published in Expert Opinion on Therapeutic Targets, Targeting the proteasome pathway, by Yokosawa and Tsukamoto explores the emergence of the proteasome and other members in the ubiquitin–proteasome pathway as novel therapeutic targets. In a related piece in Scrip World Pharmaceutical News, Informa Analyst Ian Schofield provides his Expert View on ubiquitylation as an attractive route to novel drug design.

Yokosawa and Tsukamoto review the current understanding of the ubiquitin–proteasome pathway and describe inhibitory mechanisms for tageting it, while Schofield discusses the RUBICON network and the recent creation of the Scottish Institute for Cell Signalling, which with government funding hopes to pinpoint novel drug targets for use in designing medicines for inflammation, cancer and infectious diseases.

Read both articles at:
Expert Opinion on Therapeutic Targets and
Scrip World Pharmaceutical News