Will genomic technologies change the landscape of toxicology research?

With so many drug failures due to toxicity concerns, the development of more effective approaches to toxicity testing is of utmost importance. In their recent review “Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity,” Rusyn and Hege Harrill put forward the view that systems toxicology ‘offers the promise of more accurate predictions of adverse health effects in humans.’ They conclude that ‘Translational research bridging rodent and human toxicity will be the key to the success of this field.’ What will the impact of such approaches be on current gold standard? How widely used will they become?

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