Computational Sciences in Drug Metabolism and Toxicology

This month Expert Opinion on Drug Metabolism and Toxicology is proud to introduce its first themed issue, focusing on Computational Sciences in Drug Metabolism and Toxicology.

Computational chemistry and bioinformatics have gained considerable importance in the pharmaceutical field to the extent that they are now integrated and indispensable to any R&D programme. This is particularly relevant in drug metabolism and toxicology studies, where in silico methods hold the potential to reduce the attrition rate throughout the drug development cycle and improve regulatory productivity and quality through faster, cheaper and better informed decision making.

Guest Edited by Dr Luis Valerio Jr., an internationally recognized expert in this topic, this issue is very unique and explores, among regulatory perspectives and reviews by leading experts, the variety of approaches in the field, their usage and development. Most importantly, it also stresses the limits of the tools and the need for their thorough understanding, testing and validation before implementation. In his free editorial, Dr Valerio Jr details the coverage of each article, and points out how these tools are evidence-based and represent an integrated science.

I hope you will find the articles insightful and thought provoking.

Joris Roulleau
Senior Editor